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GOT1 inhibitor-1

CAS No. 732973-87-4

GOT1 inhibitor-1 ( GOT1 inhibitor 2c )

产品货号. M24741 CAS No. 732973-87-4

GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1596 有现货
10MG ¥2657 有现货
25MG ¥4520 有现货
50MG ¥6383 有现货
100MG ¥9072 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    GOT1 inhibitor-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
  • 产品描述
    GOT1 inhibitor-1 is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.
  • 同义词
    GOT1 inhibitor 2c
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    GOT1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    732973-87-4
  • 分子量
    354.8
  • 分子式
    C19H19ClN4O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:120mg/ml(338.19mM; need ultrasonic)
  • SMILES
    O=C(Nc(cc1)ccc1Cl)N(CC1)CCN1c1c(cc[nH]2)c2ccc1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Anglin J , Zavareh R B , Sander P N , et al. Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma[J]. Bioorganic & Medicinal Chemistry Letters, 2018:S0960894X18303743.
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